PEBP1 and STC2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PEBP1	STC2
Description		phosphatidylethanolamine binding protein 1	stanniocalcin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Phosphatidylethanolamine Binding Enzyme Binding Protein Kinase Binding	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	MAPK Cascade Negative Regulation Of Endopeptidase Activity Negative Regulation Of MAPK Cascade	Cellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Gene Expression Response To Vitamin D Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia
Pathways		MAP2K and MAPK activation Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Copper
Diseases
GWAS		Blood protein levels ( 30072576) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		23 interacting genes: BRAF CACHD1 CHUK ERBB2 GRK2 GSDMB IKBKB MAP2K1 MAP3K14 MAP3K7 MAPK1 MED10 NKX3-1 NR2C2 PICK1 PPARD PRKCA PRKCB PRKCD PRKCG PRKCZ RAF1 STC2	11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN
Entrez ID		5037	8614
HPRD ID		06850	04717
Ensembl ID		ENSG00000089220	ENSG00000113739
Uniprot IDs		D9IAI1 P30086	O76061 Q6FHC9
PDB IDs		1BD9 1BEH 2L7W 2QYQ
Enriched GO Terms of Interacting Partners?
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