MYH7B and SMYD1

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		MYH7B	SMYD1
Description		myosin heavy chain 7B	SET and MYND domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Myosin Complex Myosin Filament Cardiac Myofibril	Nucleus Cytoplasm
	Molecular Function	Motor Activity Protein Binding ATP Binding Actin Filament Binding	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process		Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Bipolar disorder ( 31043756) Birth weight ( 31043758) Blood protein levels ( 28240269) Congenital left-sided heart lesions ( 26965164) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462) Fish- and plant-related diet ( 32066663) Melanoma ( 28212542) Offspring birth weight ( 31043758) Prothrombin time ( 22703881) QRS complex (Cornell) ( 27659466) QRS duration ( 30012220) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)
Interacting Genes		7 interacting genes: ETFDH PITX1 QRICH1 RBPMS SMYD1 TLE5 TNS2	44 interacting genes: ARID5A BACH2 BHLHE40 C11orf1 C11orf16 C11orf53 CCDC113 CCDC33 DISC1 DVL1 FAM166A FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44
Entrez ID		57644	150572
HPRD ID		11379	06025
Ensembl ID		ENSG00000078814	ENSG00000115593
Uniprot IDs		A7E2Y1	E9PHG3 Q5HYE8 Q8NB12
PDB IDs
Enriched GO Terms of Interacting Partners?
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