NYAP2 and AGFG1

Data Source:
BioGRID (two hybrid)

		NYAP2	AGFG1
Description		neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2	ArfGAP with FG repeats 1
Image		No pdb structure
GO Annotations	Cellular Component		Nuclear Pore Cytosol Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol 3-kinase Signaling Neuron Projection Morphogenesis	MRNA Export From Nucleus Multicellular Organism Development Spermatogenesis Cell Differentiation Positive Regulation Of GTPase Activity Membrane Organization
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Insulin levels in response to oral glucose tolerance test (fasting) ( 29093273) Menopause (age at onset) ( 23307926) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI) ( 27416945) Neurociticism ( 29500382) Smoking status (ever vs never smokers) ( 30643258) Squamous cell lung carcinoma ( 28604730) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 30910378)	Airway hyperresponsiveness ( 23984888) Asthma ( 31959851) Mild influenza (H1N1) infection ( 26379185)
Interacting Genes		6 interacting genes: AGFG1 CYFIP1 MORN4 NCKAP1 PIK3R1 WASF1	14 interacting genes: APC APP DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 PKIA POLE2 RNF216 TRIM54 VAMP7 XPO1
Entrez ID		57624	3267
HPRD ID		13867	02918
Ensembl ID		ENSG00000144460	ENSG00000173744
Uniprot IDs		Q9P242	A0A0S2Z3Y3 A0A0S2Z3Z1 A0A0S2Z444 A0A0S2Z462 P52594
PDB IDs			2D9L 2OLM 2VX8
Enriched GO Terms of Interacting Partners?
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