AGFG1 and EPS15L1

Data Source:
HPRD (two hybrid, in vivo)

		AGFG1	EPS15L1
Description		ArfGAP with FG repeats 1	epidermal growth factor receptor pathway substrate 15 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Cytosol Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit
	Molecular Function	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	MRNA Export From Nucleus Multicellular Organism Development Spermatogenesis Cell Differentiation Positive Regulation Of GTPase Activity Membrane Organization	Endocytosis Endosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Airway hyperresponsiveness ( 23984888) Asthma ( 31959851) Mild influenza (H1N1) infection ( 26379185)	Basophil count ( 32888494) Body size at age 10 ( 32376654) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494 27863252 21738480) White matter integrity ( 23218918)
Interacting Genes		14 interacting genes: APC APP DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 PKIA POLE2 RNF216 TRIM54 VAMP7 XPO1	15 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 LRRC7 NDC80 SGIP1 STON2 TRAPPC2 TRAPPC2B UBC
Entrez ID		3267	58513
HPRD ID		02918	09445
Ensembl ID		ENSG00000173744	ENSG00000127527
Uniprot IDs		A0A0S2Z3Y3 A0A0S2Z3Z1 A0A0S2Z444 A0A0S2Z462 P52594	A0A024R7G6 Q9UBC2
PDB IDs		2D9L 2OLM 2VX8
Enriched GO Terms of Interacting Partners?
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