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MRTFA and KDM3A
Data Source:
BioGRID
(pull down)
MRTFA
KDM3A
Description
myocardin related transcription factor A
lysine demethylase 3A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Histone Deacetylase Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Molecular Function
Transcription Coactivator Activity
Actin Binding
Actin Monomer Binding
Protein Binding
Leucine Zipper Domain Binding
Transcription Coregulator Activity
Iron Ion Binding
Protein Binding
Chromatin DNA Binding
Histone Demethylase Activity (H3-K9 Specific)
Androgen Receptor Binding
Dioxygenase Activity
Biological Process
Positive Regulation Of Transcription Via Serum Response Element Binding
Actin Cytoskeleton Organization
Wound Healing, Spreading Of Cells
Positive Regulation Of Transcription By RNA Polymerase II
Smooth Muscle Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Spermatid Nucleus Elongation
Hormone-mediated Signaling Pathway
Androgen Receptor Signaling Pathway
Histone H3-K9 Demethylation
Histone H3-K9 Dimethylation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Formaldehyde Biosynthetic Process
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Cold-induced Thermogenesis
Cellular Response To Leukemia Inhibitory Factor
Regulation Of Stem Cell Population Maintenance
Regulation Of Stem Cell Differentiation
Pathways
SUMOylation of transcription cofactors
RHO GTPases Activate Formins
HDMs demethylate histones
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Latrunculin B
Diseases
GWAS
Atrial fibrillation (
29892015
)
Glomerular filtration rate in chronic kidney disease (
26420894
)
Ovarian cancer (
30557369
)
Interacting Genes
10 interacting genes:
KDM3A
MRTFB
MVP
MYOCD
NCOA3
SMARCA4
SRF
SUMO1
TRIM54
UBE2I
6 interacting genes:
ETV2
H3C14
MRTFA
MRTFB
MYOCD
RIPK2
Entrez ID
57591
55818
HPRD ID
10445
11054
Ensembl ID
ENSG00000196588
ENSG00000115548
Uniprot IDs
A4FUJ8
E7ER32
Q969V6
W0Z7M9
Q9Y4C1
PDB IDs
2KVU
2KW9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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