CARNS1 and TRIP12

Data Source:
HPRD (two hybrid)

		CARNS1	TRIP12
Description		carnosine synthase 1	thyroid hormone receptor interactor 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Nucleoplasm Cytosol Nuclear Speck
	Molecular Function	ATP Binding ATPase Activity Metal Ion Binding Carnosine Synthase Activity Homocarnosine Synthase Activity	Protein Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Histidine Catabolic Process Carnosine Biosynthetic Process	Protein Polyubiquitination DNA Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Embryonic Development Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair
Pathways		Histidine catabolism	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Height ( 28552196) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494)	Carotid intima media thickness x smoking interaction ( 32117412) Estimated glomerular filtration rate ( 31152163 31015462) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653) Weight ( 28552196)
Interacting Genes		1 interacting genes: TRIP12	20 interacting genes: ATF7IP CARNS1 CDKN2A CELSR3 CLSTN1 ERG MTNR1A MTNR1B NAE1 NMI PTF1A SMAD9 SOX6 SRPK2 THRB UBC UBE2D1 UBE2D2 UBE2L3 UBE4B
Entrez ID		57571	9320
HPRD ID		13855	05144
Ensembl ID		ENSG00000172508	ENSG00000153827
Uniprot IDs		A5YM72	A0A6Q8PGG9 A0A6Q8PHK0 Q14669
PDB IDs
Enriched GO Terms of Interacting Partners?
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