MIB1 and CHST9

Data Source:
HPRD (in vitro)

		MIB1	CHST9
Description		MIB E3 ubiquitin protein ligase 1	carbohydrate sulfotransferase 9
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle	Golgi Membrane Extracellular Region Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	N-acetylgalactosamine 4-O-sulfotransferase Activity Sulfotransferase Activity
	Biological Process	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Ubiquitin-dependent Protein Catabolic Process Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis	Sulfur Compound Metabolic Process Carbohydrate Biosynthetic Process Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Biosynthetic Process Hormone Biosynthetic Process
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Severe progression in rheumatoid arthritis ( 29065906)	Blood protein levels ( 30072576 29875488) Breast cancer ( 29059683 23535729) Bronchopulmonary dysplasia ( 23897914) Dental caries ( 23259602) Metabolite levels ( 23823483) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		15 interacting genes: AZI2 BLM DAB2 DAPK1 EPB41L4A GABARAP JAG1 SNX5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W	1 interacting genes: LHCGR
Entrez ID		57534	83539
HPRD ID		06660	13058
Ensembl ID		ENSG00000101752	ENSG00000154080
Uniprot IDs		Q86YT6	A0A024RC28 Q7L1S5
PDB IDs		4TSE 4XI6 4XI7 4XIB
Enriched GO Terms of Interacting Partners?
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