CHST9 and LHCGR

Data Source:
HPRD (in vitro)

		CHST9	LHCGR
Description		carbohydrate sulfotransferase 9	luteinizing hormone/choriogonadotropin receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Integral Component Of Membrane	Endosome Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	N-acetylgalactosamine 4-O-sulfotransferase Activity Sulfotransferase Activity	Luteinizing Hormone Receptor Activity G Protein-coupled Peptide Receptor Activity Choriogonadotropin Hormone Receptor Activity Choriogonadotropin Hormone Binding
	Biological Process	Sulfur Compound Metabolic Process Carbohydrate Biosynthetic Process Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Biosynthetic Process Hormone Biosynthetic Process	Ovarian Follicle Development G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Male Gonad Development Hormone-mediated Signaling Pathway Ovulation Cycle Process Male Genitalia Development Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Luteinizing Hormone Signaling Pathway Cognition Cellular Response To Gonadotropin Stimulus Cellular Response To Luteinizing Hormone Stimulus
Pathways			Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Goserelin Menotropins Lutropin alfa Cetrorelix Choriogonadotropin alfa Buserelin Chorionic Gonadotropin (Human)
Diseases			46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS) Premature ovarian failure Precocious puberty, including: Central precocious puberty (CEPREPU); Familial male precocious puberty (FMPP)
GWAS		Blood protein levels ( 30072576 29875488) Breast cancer ( 29059683 23535729) Bronchopulmonary dysplasia ( 23897914) Dental caries ( 23259602) Metabolite levels ( 23823483) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)	Body mass index ( 28892062) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 22885925 21151128) Sex hormone-binding globulin levels ( 22829776) Triglyceride levels ( 32154731)
Interacting Genes		1 interacting genes: LHCGR	11 interacting genes: ARRB2 CANX CGA CGB3 CHST9 GIPC1 GNAI2 GNAS LHB SLC9A3R1 TSHR
Entrez ID		83539	3973
HPRD ID		13058	01073
Ensembl ID		ENSG00000154080	ENSG00000138039
Uniprot IDs		A0A024RC28 Q7L1S5	P22888
PDB IDs			1LUT 1XUL
Enriched GO Terms of Interacting Partners?
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