AARS2 and MEGF10

Data Source:
HPRD (two hybrid)

		AARS2	MEGF10
Description		alanyl-tRNA synthetase 2, mitochondrial	multiple EGF like domains 10
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Phagocytic Cup Plasma Membrane Integral Component Of Membrane Cell Projection
	Molecular Function	TRNA Binding Aminoacyl-tRNA Editing Activity Alanine-tRNA Ligase Activity Protein Binding ATP Binding Zinc Ion Binding Amino Acid Binding	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding
	Biological Process	TRNA Modification Alanyl-tRNA Aminoacylation Mitochondrial Alanyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Alanine
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)
Interacting Genes		3 interacting genes: EHHADH MEGF10 YWHAQ	23 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1
Entrez ID		57505	84466
HPRD ID		12397	14384
Ensembl ID		ENSG00000124608	ENSG00000145794
Uniprot IDs		Q5JTZ9	Q96KG7
PDB IDs		6NLQ 6NLY 6NOW
Enriched GO Terms of Interacting Partners?
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