ZNF512B and XPC

Data Source:
BioGRID (two hybrid)

		ZNF512B	XPC
Description		zinc finger protein 512B	XPC complex subunit, DNA damage recognition and repair factor
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GO Annotations	Cellular Component	Nucleoplasm	Nucleotide-excision Repair Complex Nucleotide-excision Repair Factor 2 Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle XPC Complex Site Of DNA Damage
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Heteroduplex DNA Loop Binding Bubble DNA Binding Damaged DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity Protein Binding Protein-containing Complex Binding
	Biological Process		Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Pyrimidine Dimer Repair By Nucleotide-excision Repair DNA Repair Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Mismatch Repair Response To UV-B Response To Auditory Stimulus Intra-S DNA Damage Checkpoint Response To Drug Positive Regulation Of Transcription, DNA-templated Global Genome Nucleotide-excision Repair UV-damage Excision Repair Regulation Of Mitotic Cell Cycle Phase Transition UV-damage Excision Repair, DNA Incision
Pathways			SUMOylation of DNA damage response and repair proteins DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases			Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
GWAS		Birth weight ( 31043758) Mean platelet volume ( 32888494) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		71 interacting genes: AJUBA ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BANP BRD1 BTBD2 C11orf68 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 GOLGA2 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MDFI MEOX2 MTUS2 MYH10 NACC1 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RABEP1 RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2 ZNF143 ZYX	15 interacting genes: CETN2 DDB2 ERCC3 GTF2H1 LSM3 MDM2 PSMD4 RAD23A RAD23B RPA1 SMAD1 TDG USP7 XPA ZNF512B
Entrez ID		57473	7508
HPRD ID		13840	02046
Ensembl ID		ENSG00000196700	ENSG00000154767
Uniprot IDs		Q96KM6	Q01831 X5DRB1
PDB IDs		2GQJ	2A4J 2GGM 2OBH 2RVB
Enriched GO Terms of Interacting Partners?
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