Description |
protein tyrosine kinase 2 |
phosphoinositide-3-kinase regulatory subunit 3 |
Image |
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No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Body mass index ( 26426971 28448500)
- Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
- Body mass index in physically active individuals ( 28448500)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Breast cancer ( 29059683)
- Cortical surface area (min-P) ( 32665545)
- Cortical surface area (MOSTest) ( 32665545)
- Cortical thickness (min-P) ( 32665545)
- Cortical thickness (MOSTest) ( 32665545)
- Diastolic blood pressure ( 30224653)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Estimated glomerular filtration rate ( 31152163)
- Lymphocyte percentage of white cells ( 32888494)
- Metabolite levels ( 23823483)
- Neutrophil count ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
- Red cell distribution width ( 32888494)
- Sodium levels ( 29403010)
- Subcortical volume (min-P) ( 32665545)
- Subcortical volume (MOSTest) ( 32665545)
- Sum neutrophil eosinophil counts ( 27863252)
- White blood cell count ( 32888494 27863252)
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Interacting Genes |
113 interacting genes:
ACTN1
APP
ARHGAP26
ASAP1
ATG12
BBS10
BCAR1
BIN1
BMX
CCR5
CD47
CD79B
CIB1
CRK
CSK
CSPG4
CXCR4
DCC
DDX39A
DEF6
DLGAP3
DNM2
DOK4
EEF1G
EFS
EGFR
EPHA2
EPHB2
EPS8L2
ERBB2
ERBB3
EZR
F13A1
FBP1
FGR
FLT1
FLT4
FYN
GIT1
GRB2
GRB7
GSK3B
GZMB
HES1
IGHM
INSR
IRS1
ITGAV
ITGB1
ITGB2
ITGB3
ITGB4
ITGB5
JAK2
KCNMA1
LCK
LPXN
LYN
MAPK8IP3
MDM2
MICAL1
NACAD
NASP
NCK1
NCK2
NEDD8
NEDD9
NEO1
PDGFRB
PIAS1
PIK3R1
PIK3R3
PKD1
PLCG1
PPP1CB
PTEN
PTK2B
PTPN11
PTPN12
PTPRH
PXN
RAC1
RB1CC1
RET
RIPK1
ROCK1
SAE1
SELE
SH2D1A
SH2D1B
SHC1
SOCS1
SOCS2
SOCS3
SORBS1
SRC
SRPK1
STAT1
SYK
TGFB1I1
TLN1
TNFRSF1A
TNS1
TNS3
TP53
TRIM15
TRIO
TRIP6
TSC2
VCL
YES1
ZFYVE21
ZNF331
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124 interacting genes:
ABCB6
ABL2
AMBP
ANKS1A
ANTKMT
AR
ARID4B
AUNIP
AXL
BLK
BLZF1
BRK1
BTK
C3orf36
C9orf24
CAMK1
CCDC14
CCDC196
CCDC33
CCDC89
CEP126
CEP19
CHRDL2
CLNK
CRBN
CRK
DARS1
DCAF8
DISC1
DRAP1
DSN1
E2F6
EGFR
ENKD1
ERBB2
ERBB3
ERBB4
ESR1
FAM166B
FBN3
FER
FGB
FNDC8
FOXO1
FSD2
FYN
GAB1
GC
GRB2
HROB
HSH2D
IGF1R
INSR
IQUB
IRS1
IRS2
ITGB3BP
KARS1
KHDRBS1
KIAA0408
KIT
KLC2
KLF15
KMT2B
L3MBTL3
LAP3
LNX2
LUC7L2
MBIP
MECOM
MET
MICAL1
MTF2
NAB2
NCK1
NEBL
NEDD9
ORM1
PACRGL
PBX4
PCDHB5
PDGFRB
PELO
PIK3CA
PIK3CD
PLAAT4
PLB1
PLEKHF2
PPARA
PRKAR1B
PSME1
PTK2
QARS1
RB1
RING1
RUSC1
SERF1A
SERTAD2
SOCS6
SPATA32
SRC
SSBP4
STAT3
STAT5B
TASOR2
TEC
TERF2
TNK2
TNNC2
TNNI1
TRIM54
TRMT2A
TSPAN2
USP2
VBP1
VCP
WRNIP1
YES1
YPEL3
ZBTB18
ZMAT1
ZNF281
ZNF451
ZNF620
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Entrez ID |
5747 |
8503 |
HPRD ID |
02859 |
05831 |
Ensembl ID |
ENSG00000169398
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ENSG00000117461
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Uniprot IDs |
Q05397
Q59GM6
Q59GN8
Q658W2
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B4DXM8
Q68CY7
Q7Z3W2
Q8N381
Q92569
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PDB IDs |
1K04
1K05
1MP8
1OW6
1OW7
1OW8
2ETM
2IJM
3B71
3BZ3
3PXK
3S9O
4EBV
4EBW
4GU6
4GU9
4I4E
4I4F
4K8A
4K9Y
4KAB
4KAO
4NY0
4Q9S
6I8Z
6LES
6PW8
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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