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PTBP1 and MIR15A
Data Source:
BioGRID
(unspecified method)
PTBP1
MIR15A
Description
polypyrimidine tract binding protein 1
microRNA 15a
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Membrane
Extracellular Exosome
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Pre-mRNA Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Negative Regulation Of RNA Splicing
Positive Regulation Of Protein Dephosphorylation
Regulation Of RNA Splicing
Regulation Of Cell Differentiation
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
IRES-dependent Viral Translational Initiation
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Hematocrit (
32888494
27863252
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
102 interacting genes:
APBB1
APP
CALCOCO2
CASP3
FUS
H3-4
HIF1A
HMGA1
HMGA2
HNRNPAB
HNRNPL
IL7R
LINC00839
LINC01554
MARK4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NONO
PCBP1
PCBP2
PCBP3
PRKACA
QKI
RAVER1
RAVER2
RBFOX2
RBM10
SFPQ
SNRPA
SRPK2
SUMO2
ZMYM2
73 interacting genes:
AIMP1
AIMP2
C1QBP
CPSF1
DARS1
DDX1
DDX21
DDX3X
DDX49
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PUF60
QARS1
RARS1
RBM14
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM71
TRMT10C
UPF1
UTP20
YBX1
YBX3
ZNF346
Entrez ID
5725
406948
HPRD ID
02823
Ensembl ID
ENSG00000011304
ENSG00000283785
Uniprot IDs
P26599
PDB IDs
1QM9
1SJQ
1SJR
2AD9
2ADB
2ADC
2EVZ
2N3O
3ZZY
3ZZZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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