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PTBP1 and MIR206
Data Source:
BioGRID
(unspecified method)
PTBP1
MIR206
Description
polypyrimidine tract binding protein 1
microRNA 206
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Membrane
Extracellular Exosome
RISC Complex
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Pre-mRNA Binding
MRNA 3'-UTR Binding
Protein Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Negative Regulation Of RNA Splicing
Positive Regulation Of Protein Dephosphorylation
Regulation Of RNA Splicing
Regulation Of Cell Differentiation
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
IRES-dependent Viral Translational Initiation
Positive Regulation Of Cell Fate Commitment
Negative Regulation Of Gene Expression
Positive Regulation Of Myotube Differentiation
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Tumor Necrosis Factor Production
Gene Silencing By MiRNA
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Neuroinflammatory Response
Positive Regulation Of Amyloid-beta Formation
Pathways
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Hematocrit (
32888494
27863252
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
102 interacting genes:
APBB1
APP
CALCOCO2
CASP3
FUS
H3-4
HIF1A
HMGA1
HMGA2
HNRNPAB
HNRNPL
IL7R
LINC00839
LINC01554
MARK4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NONO
PCBP1
PCBP2
PCBP3
PRKACA
QKI
RAVER1
RAVER2
RBFOX2
RBM10
SFPQ
SNRPA
SRPK2
SUMO2
ZMYM2
78 interacting genes:
ADARB1
AIMP1
AQR
C1QBP
CELF1
CPSF1
CSTF1
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LCORL
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
NOL4L
NONO
NUDT21
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUM1
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCB
SF3A3
SF3B1
SF3B2
SF3B3
SFPQ
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
5725
406989
HPRD ID
02823
Ensembl ID
ENSG00000011304
ENSG00000207604
Uniprot IDs
P26599
PDB IDs
1QM9
1SJQ
1SJR
2AD9
2ADB
2ADC
2EVZ
2N3O
3ZZY
3ZZZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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