PARP11 and GTPBP3

Data Source:
HPRD (two hybrid)

		PARP11	GTPBP3
Description		poly(ADP-ribose) polymerase family member 11	GTP binding protein 3, mitochondrial
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body	Cytoplasm Mitochondrion
	Molecular Function	NAD+ ADP-ribosyltransferase Activity Protein ADP-ribosylase Activity	GTPase Activity Protein Binding GTP Binding
	Biological Process	Nuclear Envelope Organization Spermatogenesis Protein Transport Cell Differentiation MRNA Transport Protein Auto-ADP-ribosylation Protein Mono-ADP-ribosylation	TRNA Wobble Uridine Modification TRNA Methylation
Pathways			tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Colorectal cancer ( 23263487) Emotional lability in attention deficit hyperactivity disorder ( 31085060) Fasting insulin (dietary factor interaction) ( 24204828) Hematocrit ( 29403010) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494) Pulse pressure ( 27841878) Red blood cell count ( 29403010) Total hippocampal volume ( 30279459) White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)	Mitochondrial DNA copy number ( 30704525)
Interacting Genes		7 interacting genes: DTX3 GTPBP3 HOOK2 LHX3 LHX4 MDFI TRIP13	28 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774
Entrez ID		57097	84705
HPRD ID		15101	12255
Ensembl ID		ENSG00000111224	ENSG00000130299
Uniprot IDs		Q9NR21	B7Z563 Q969Y2
PDB IDs		2DK6
Enriched GO Terms of Interacting Partners?
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