PLSCR2 and LCE3A

Data Source:
BioGRID (two hybrid)

		PLSCR2	LCE3A
Description		phospholipid scramblase 2	late cornified envelope 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Calcium Ion Binding Protein Binding Phospholipid Scramblase Activity	Protein Binding
	Biological Process	Plasma Membrane Phospholipid Scrambling	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Hip circumference ( 28552196)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)
Interacting Genes		14 interacting genes: AQP1 BSND COQ9 EP300 FAM221B GNG13 HOXA1 LCE1A LCE3A LCE3E LCE5A LYPD1 OTX1 POU4F2	61 interacting genes: ADAMTSL4 ALPP CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE3B MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VWC2 VWC2L
Entrez ID		57047	353142
HPRD ID		09621	13973
Ensembl ID		ENSG00000163746	ENSG00000185962
Uniprot IDs		Q9NRY7	Q5TA76
PDB IDs
Enriched GO Terms of Interacting Partners?
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