LCE3A and CHIC2

Data Source:
BioGRID (two hybrid)

		LCE3A	CHIC2
Description		late cornified envelope 3A	cysteine rich hydrophobic domain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Apparatus Golgi-associated Vesicle Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Biological_process
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)	Blood pressure ( 21909110) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulse pressure ( 28739976 30487518) Serum metabolite levels (CMS) ( 31636271) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		61 interacting genes: ADAMTSL4 ALPP CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE3B MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VWC2 VWC2L	65 interacting genes: ADAMTSL4 AGXT AXIN2 C1QTNF2 CARD10 CATSPER1 CBY2 CDR2 CEP44 CYSRT1 DNAL4 FBLN1 GMCL1 HOXA1 ITSN2 KANK2 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-2 LCE1A LCE1C LCE1F LCE2C LCE3A LCE3C LCE3D LCE5A LCN2 LZTS2 MDFI MEOX2 MTUS2 MYF5 MYPOP NBPF19 NDUFB7 NOTCH2NLA OTX1 PLEKHF1 PLEKHF2 PLEKHG4 PNMA1 POU4F2 PPARA REL SCNM1 SDCBP TCF4 TOP3B TUBGCP4 U2AF2 ZNF330 ZNF837
Entrez ID		353142	26511
HPRD ID		13973	10373
Ensembl ID		ENSG00000185962	ENSG00000109220
Uniprot IDs		Q5TA76	Q9UKJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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