LCE3A and KRTAP5-4

Data Source:
BioGRID (two hybrid)

		LCE3A	KRTAP5-4
Description		late cornified envelope 3A	keratin associated protein 5-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Keratinization
Pathways		Formation of the cornified envelope	Keratinization
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)
Interacting Genes		61 interacting genes: ADAMTSL4 ALPP CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE3B MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VWC2 VWC2L	36 interacting genes: ADAMTSL4 BAG5 CATSPER1 CRCT1 CREB5 CRY2 CYSRT1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE4A LCE5A MEOX2 NBPF19 NOTCH2NLA NUFIP2 PLEKHF2 POU4F2 RGS17 SMCP UBE2I
Entrez ID		353142	387267
HPRD ID		13973	12396
Ensembl ID		ENSG00000185962	ENSG00000241598
Uniprot IDs		Q5TA76	A8MUN0 Q6L8H1
PDB IDs
Enriched GO Terms of Interacting Partners?
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