TWSG1 and GPRC5D

Data Source:
BioGRID (two hybrid)

		TWSG1	GPRC5D
Description		twisted gastrulation BMP signaling modulator 1	G protein-coupled receptor class C group 5 member D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding Transforming Growth Factor Beta Binding	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity
	Biological Process	Ossification Mesoderm Formation Negative Regulation Of Cytokine Production Transforming Growth Factor Beta Receptor Signaling Pathway Salivary Gland Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Hemopoiesis Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Interacting Genes		10 interacting genes: BMP1 BMP4 CHRD FAM209A FNDC9 GJA8 GPRC5D LRRC4C SGTA TNS2	30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1
Entrez ID		57045	55507
HPRD ID		05443	07604
Ensembl ID		ENSG00000128791	ENSG00000111291
Uniprot IDs		Q9GZX9	Q9NZD1
PDB IDs
Enriched GO Terms of Interacting Partners?
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