PRTFDC1 and SIK1B

Data Source:
BioGRID (two hybrid)

		PRTFDC1	SIK1B
Description		phosphoribosyl transferase domain containing 1	salt inducible kinase 1B (putative)
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process	Protein Phosphorylation Intracellular Signal Transduction Cellular Response To Glucose Starvation
Pathways			Circadian Clock
Drugs			Dabrafenib Fostamatinib
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		19 interacting genes: CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 SIK1B SPG21 STAT5A TCL1A TMEM14B VWA5A	6 interacting genes: GINS4 LHX8 MESD PITX1 PRTFDC1 TIMM10
Entrez ID		56952	102724428
HPRD ID		17917
Ensembl ID		ENSG00000099256	ENSG00000275993
Uniprot IDs		Q9NRG1	A0A0B4J2F2 P57059
PDB IDs		2JBH
Enriched GO Terms of Interacting Partners?
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