SIK1B and PRTFDC1

Data Source:
BioGRID (two hybrid)

		SIK1B	PRTFDC1
Description		salt inducible kinase 1B (putative)	phosphoribosyl transferase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Protein Phosphorylation Intracellular Signal Transduction Cellular Response To Glucose Starvation	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process
Pathways		Circadian Clock
Drugs		Dabrafenib Fostamatinib
Diseases
GWAS			Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		6 interacting genes: GINS4 LHX8 MESD PITX1 PRTFDC1 TIMM10	19 interacting genes: CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 SIK1B SPG21 STAT5A TCL1A TMEM14B VWA5A
Entrez ID		102724428	56952
HPRD ID			17917
Ensembl ID		ENSG00000275993	ENSG00000099256
Uniprot IDs		A0A0B4J2F2 P57059	Q9NRG1
PDB IDs			2JBH
Enriched GO Terms of Interacting Partners?
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