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AGPAT4 and SLC7A8
Data Source:
BioGRID
(two hybrid)
AGPAT4
SLC7A8
Description
1-acylglycerol-3-phosphate O-acyltransferase 4
solute carrier family 7 member 8
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Endomembrane System
Integral Component Of Membrane
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Basal Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Microvillus Membrane
Molecular Function
1-acylglycerol-3-phosphate O-acyltransferase Activity
Protein Binding
Transferase Activity, Transferring Acyl Groups
Protein Binding
Organic Cation Transmembrane Transporter Activity
Amino Acid Transmembrane Transporter Activity
Neutral Amino Acid Transmembrane Transporter Activity
L-amino Acid Transmembrane Transporter Activity
L-alanine Transmembrane Transporter Activity
Glycine Transmembrane Transporter Activity
L-leucine Transmembrane Transporter Activity
Thyroid Hormone Transmembrane Transporter Activity
Toxin Transmembrane Transporter Activity
Peptide Antigen Binding
Biological Process
Phosphatidic Acid Biosynthetic Process
Phospholipid Biosynthetic Process
CDP-diacylglycerol Biosynthetic Process
Amino Acid Transmembrane Transport
Amino Acid Transport
Response To Toxic Substance
Organic Cation Transport
Neutral Amino Acid Transport
Glycine Transport
Leucine Transport
Tryptophan Transport
Valine Transport
Proline Transmembrane Transport
Leukocyte Migration
Metal Ion Homeostasis
Thyroid Hormone Transport
Amino Acid Import Across Plasma Membrane
Leucine Import Across Plasma Membrane
Transport Across Blood-brain Barrier
Toxin Transport
L-leucine Import Across Plasma Membrane
L-alanine Import Across Plasma Membrane
Pathways
Synthesis of PA
Basigin interactions
Amino acid transport across the plasma membrane
Drugs
Phenylalanine
Alanine
Diseases
GWAS
Anxiety in major depressive disorder (
24047446
)
Diastolic blood pressure (
30224653
)
Energy expenditure (24h) (
28476931
)
Fear of pain (
28701861
)
Lipoprotein (a) - cholesterol levels (
25575512
)
Lipoprotein (a) levels (
26377243
)
Metabolite levels (
23823483
)
Interacting Genes
28 interacting genes:
AQP12B
AQP6
CNR2
CREB3L1
ERGIC3
FCGR2A
FCRL3
FFAR2
GPR101
HSD17B11
HSD17B13
JAGN1
LEPROTL1
LEUTX
LRRC25
MFF
MFSD14B
MGST3
REEP4
REL
RETREG3
SCN3B
SLC35C2
SLC7A8
SPACA1
TMEM14B
TMEM31
TMX2
26 interacting genes:
ABHD16A
AGPAT4
AQP6
COMT
DERL1
FXYD6-FXYD2
MFF
MFSD3
NDUFA3
NINJ2
REEP4
SIGLEC5
SLC25A46
SLC30A2
SLC3A1
SLC3A2
SMPD2
SNORC
SYCE1L
SYNJ2BP
TMEM14B
TMEM208
TMEM60
TMEM65
YIPF1
YIPF6
Entrez ID
56895
23428
HPRD ID
12437
11971
Ensembl ID
ENSG00000026652
ENSG00000092068
Uniprot IDs
Q9NRZ5
Q53EM9
Q9UHI5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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