KLK10 and CRYBA1

Data Source:
BioGRID (proximity labelling technology)

		KLK10	CRYBA1
Description		kallikrein related peptidase 10	crystallin beta A1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Secretory Granule	Nucleus Cytoplasm
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Proteolysis Cell Cycle	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: BCAP31 LRIF1	24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3
Entrez ID		5655	1411
HPRD ID		04054	00429
Ensembl ID		ENSG00000129451	ENSG00000108255
Uniprot IDs		O43240	P05813
PDB IDs		5LPE 5LPF
Enriched GO Terms of Interacting Partners?
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