KLK10 and BCAP31

Data Source:
BioGRID (two hybrid)

		KLK10	BCAP31
Description		kallikrein related peptidase 10	B cell receptor associated protein 31
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GO Annotations	Cellular Component	Extracellular Region Secretory Granule	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding
	Biological Process	Proteolysis Cell Cycle	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Targeting To Mitochondrion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Viral Process Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Response To Endoplasmic Reticulum Stress Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Apoptotic cleavage of cellular proteins Apoptotic execution phase Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		2 interacting genes: BCAP31 LRIF1	30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		5655	10134
HPRD ID		04054	02319
Ensembl ID		ENSG00000129451	ENSG00000185825
Uniprot IDs		O43240	P51572
PDB IDs		5LPE 5LPF	4JZL 4JZP
Enriched GO Terms of Interacting Partners?
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