CRYBA1 and CRYBB1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CRYBA1	CRYBB1
Description		crystallin beta A1	crystallin beta B1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis	Lens Development In Camera-type Eye Visual Perception
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)	Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3	10 interacting genes: ABCC8 AP1B1 CRYBA1 CRYBA2 CRYBA4 DDIT4L EXOC5 GAS8 TERF1 TERF2IP
Entrez ID		1411	1414
HPRD ID		00429	09021
Ensembl ID		ENSG00000108255	ENSG00000100122
Uniprot IDs		P05813	P53674
PDB IDs			1OKI
Enriched GO Terms of Interacting Partners?
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