PRSS8 and SLC13A1

Data Source:
BioGRID (protein complementation assay)

		PRSS8	SLC13A1
Description		serine protease 8	solute carrier family 13 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity Sodium Channel Regulator Activity	Sodium:sulfate Symporter Activity
	Biological Process	Proteolysis Positive Regulation Of Sodium Ion Transport Cornification	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		Formation of the cornified envelope	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs		1-[4-(hydroxymethyl)phenyl]guanidine
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		2 interacting genes: ATF7IP SLC13A1	31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3
Entrez ID		5652	6561
HPRD ID		02895	08394
Ensembl ID		ENSG00000052344	ENSG00000081800
Uniprot IDs		Q16651	A4D0X1 Q2NKK0 Q9BZW2
PDB IDs		3DFJ 3DFL 3E0N 3E0P 3E16 3E1X 3FVF 3GYL 3GYM
Enriched GO Terms of Interacting Partners?
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