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RPRM and CLDN5
Data Source:
BioGRID
(two hybrid)
RPRM
CLDN5
Description
reprimo, TP53 dependent G2 arrest mediator homolog
claudin 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Integral Component Of Membrane
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Apicolateral Plasma Membrane
Cell Junction
Cortical Actin Cytoskeleton
Tight Junction
Molecular Function
Protein Binding
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Biological Process
Cell Cycle Arrest
Regulation Of Mitotic Cell Cycle
Outflow Tract Morphogenesis
Cell-cell Junction Assembly
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Learning
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Maintenance Of Blood-brain Barrier
Negative Regulation Of Vascular Permeability
Roof Of Mouth Development
Face Morphogenesis
Bicellular Tight Junction Assembly
Tight Junction Assembly
Positive Regulation Of Establishment Of Endothelial Barrier
Positive Regulation Of Bicellular Tight Junction Assembly
Establishment Of Blood-retinal Barrier
Regulation Of Bicellular Tight Junction Assembly
Pathways
Tight junction interactions
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Anti-saccade response (
29064472
)
Blood trace element (Zn levels) (
23720494
)
Heel bone mineral density (
30598549
)
Lung cancer (
28604730
)
Interacting Genes
79 interacting genes:
ADGRG3
AMIGO1
AQP6
ARFIP1
ASGR2
BNIP3
BSCL2
BTNL9
C16orf54
CD33
CD53
CD69
CLDN5
CLDN7
CLDN9
CLEC17A
CLEC2D
COQ8A
CREB3
CXorf66
EHHADH
EMP1
FAM209A
FAM210B
FATE1
FBXL19
FCGR1A
FFAR2
FGD2
FKBP7
FNDC9
GAD2
GJA5
GJB3
GJB5
GNG13
GPR37L1
GPR42
HHLA2
HIP1
HSD17B13
KCNJ6
LAPTM5
LHFPL5
LMNA
LPAR6
MPP1
MS4A4A
MTIF3
OPRD1
OPRM1
PBX3
PDZK1IP1
PLEKHF2
PNKP
SCAND1
SDCBP
SENP2
SLC18A1
SLC38A1
SMIM3
SNX11
SNX12
SNX3
SPACA1
SPCS1
STOM
SUSD3
SYT16
TM4SF18
TMEM106C
TMEM237
TMEM79
TMEM80
TMEM86B
TSPO2
TTPA
WDFY2
ZDHHC22
40 interacting genes:
AQP1
BTNL8
CCDC167
CLDN3
CLRN2
CNPY3
CORIN
CTRL
CXCL9
CYB561A3
EFNA5
EHHADH
ERG28
ERMP1
FXYD6-FXYD2
GYPA
LAT
LHFPL5
MIP
MPDZ
PLP2
PLPPR2
PMP22
RPRM
SFTPC
SGCG
SLC35B4
SMIM3
TECR
TF
TJP1
TMEM128
TMEM140
TMEM14C
TMEM182
TMEM190
TMEM222
TSPAN2
VAMP5
YIPF1
Entrez ID
56475
7122
HPRD ID
18002
03654
Ensembl ID
ENSG00000177519
ENSG00000184113
Uniprot IDs
Q9NS64
D3DX19
O00501
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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