CFC1 and PLEKHB2

Data Source:
HPRD (in vitro)

		CFC1	PLEKHB2
Description		cripto, FRL-1, cryptic family 1	pleckstrin homology domain containing B2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region Plasma Membrane Cell Surface Anchored Component Of Membrane	Integral Component Of Membrane Recycling Endosome Membrane
	Molecular Function	Molecular_function Signaling Receptor Binding Nodal Binding Activin Receptor Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Blood Vessel Development Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway Anatomical Structure Development	Regulation Of Cell Differentiation
Pathways		Signaling by NODAL Regulation of signaling by NODAL
Drugs
Diseases		Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS
Interacting Genes			49 interacting genes: ATF7IP BHLHE40 C1orf94 CD68 CDA CLDN19 DAZAP2 DCUN1D1 EMP1 EMP3 EPN1 EPN2 FAM168A FOXD4L3 GGA3 GJB2 GLIS2 HEY1 HEYL HGS HIVEP1 MAP3K1 MED25 MTURN NTAQ1 OTUB2 PIP4P1 PITX1 POGZ PROP1 RHBDD1 RPS27A SFT2D1 SNRPB STAM2 SYNGR1 TAX1BP1 TRARG1 UBA52 UBAC1 UBAP2 UBASH3A UBB UBC UBQLN2 UBXN6 UPF1 YOD1 ZFAND2A
Entrez ID		55997	55041
HPRD ID		05548	15144
Ensembl ID		ENSG00000136698	ENSG00000115762
Uniprot IDs		A0A087WWV2 A0A087WX98 P0CG37	A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7
PDB IDs			3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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