PBK and ZBTB26

Data Source:
BioGRID (two hybrid)

		PBK	ZBTB26
Description		PDZ binding kinase	zinc finger and BTB domain containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cellular_component Nucleoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MAPK Cascade Activation Of MAPK Activity Mitotic Cell Cycle Negative Regulation Of Protein Phosphorylation Protein Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To UV Negative Regulation Of Inflammatory Response	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways
Drugs
Diseases
GWAS			Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		19 interacting genes: ARAF CCNB1 CDK1 CEP126 DLG1 GPRASP1 GPS2 H2AX LNX1 MCRS1 PTEN RAF1 SMAD4 TERT TP53 TRIM37 ZBTB26 ZFP64 ZNF526	35 interacting genes: AXIN1 CARD10 CDC37 CDC7 CYP2W1 DAXX DVL3 EHHADH EIF6 GAS8 GIPC2 HMBOX1 L3MBTL2 LNX1 MORF4L1 MORF4L2 PBK PPL RAD23A RAD54L2 RNF4 SOX5 SUMO1 SUMO1P1 TRAF4 TRIM41 TSGA10 UBE2I ZBTB12 ZBTB34 ZBTB48 ZBTB6 ZBTB9 ZMYM5 ZNF408
Entrez ID		55872	57684
HPRD ID		17822	15692
Ensembl ID		ENSG00000168078	ENSG00000171448
Uniprot IDs		Q96KB5 V9HWH0	Q9HCK0
PDB IDs		5J0A
Enriched GO Terms of Interacting Partners?
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