PBK and CEP126

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PBK	CEP126
Description		PDZ binding kinase	centrosomal protein 126
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Centrosome Midbody Ciliary Base
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	MAPK Cascade Activation Of MAPK Activity Mitotic Cell Cycle Negative Regulation Of Protein Phosphorylation Protein Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To UV Negative Regulation Of Inflammatory Response	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: ARAF CCNB1 CDK1 CEP126 DLG1 GPRASP1 GPS2 H2AX LNX1 MCRS1 PTEN RAF1 SMAD4 TERT TP53 TRIM37 ZBTB26 ZFP64 ZNF526	87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZBED8 ZNF24
Entrez ID		55872	57562
HPRD ID		17822	17212
Ensembl ID		ENSG00000168078	ENSG00000110318
Uniprot IDs		Q96KB5 V9HWH0	Q9P2H0
PDB IDs		5J0A
Enriched GO Terms of Interacting Partners?
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