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VPS11 and UVRAG
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
VPS11
UVRAG
Description
VPS11 core subunit of CORVET and HOPS complexes
UV radiation resistance associated
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Autophagosome
Clathrin-coated Vesicle
Endocytic Vesicle
HOPS Complex
Late Endosome Membrane
Lytic Vacuole
Autophagosome Membrane
Chromosome, Centromeric Region
Cytoplasm
Lysosome
Endosome
Early Endosome
Late Endosome
Endoplasmic Reticulum
Centrosome
Midbody
Phagocytic Vesicle
DNA-dependent Protein Kinase Complex
Molecular Function
Nucleotide Binding
Protein Binding
Protein Domain Specific Binding
Syntaxin Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
SNARE Binding
Protein Binding
SH3 Domain Binding
Biological Process
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Autophagy
Endosome Organization
Vacuole Organization
Endosome To Lysosome Transport
Protein Ubiquitination
Regulation Of Protein Stability
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Endosomal Vesicle Fusion
Regulation Of SNARE Complex Assembly
Regulation Of Organelle Assembly
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Early Endosome To Late Endosome Transport
DNA Repair
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Autophagy
Spindle Organization
Chromosome Segregation
Centrosome Cycle
Regulation Of Cytokinesis
Receptor Catabolic Process
SNARE Complex Assembly
Viral Entry Into Host Cell
Maintenance Of Golgi Location
Regulation Of Protein Serine/threonine Kinase Activity
Multivesicular Body Sorting Pathway
Autophagosome Maturation
Double-strand Break Repair Via Classical Nonhomologous End Joining
Positive Regulation Of Autophagosome Maturation
Pathways
Macroautophagy
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Body mass index (
29273807
)
Coronary artery disease (
29212778
33020668
)
HDL cholesterol levels (
32203549
)
Plateletcrit (
32888494
)
Asthma (
31619474
)
HDL cholesterol (
30275531
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
33 interacting genes:
BCAR1
BMI1
ECPAS
EZR
GGA3
KDM1A
KRTAP10-3
KRTAP10-8
LRSAM1
LSM1
MARK3
MON1B
MSN
RAB7A
RDX
RILP
RNF181
STX1A
STX6
STX7
STX8
TFAP2B
TRIM32
TSG101
UBE2D2
UBE2L3
UBE2U
UVRAG
VPS16
VPS18
VPS33A
VPS39
VPS45
7 interacting genes:
CSNK1A1
MTOR
VPS11
VPS16
VPS18
VPS33B
ZRANB1
Entrez ID
55823
7405
HPRD ID
12258
03929
Ensembl ID
ENSG00000160695
ENSG00000198382
Uniprot IDs
A0A087WXL6
B7Z879
Q9H270
Q9P2Y5
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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