UVRAG and VPS33B

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		UVRAG	VPS33B
Description		UV radiation resistance associated	VPS33B late endosome and lysosome associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lytic Vacuole Autophagosome Membrane Chromosome, Centromeric Region Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Centrosome Midbody Phagocytic Vesicle DNA-dependent Protein Kinase Complex	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Golgi Apparatus Clathrin-coated Vesicle HOPS Complex Platelet Alpha Granule Early Endosome Membrane Late Endosome Membrane CORVET Complex Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	SNARE Binding Protein Binding SH3 Domain Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Autophagy Spindle Organization Chromosome Segregation Centrosome Cycle Regulation Of Cytokinesis Receptor Catabolic Process SNARE Complex Assembly Viral Entry Into Host Cell Maintenance Of Golgi Location Regulation Of Protein Serine/threonine Kinase Activity Multivesicular Body Sorting Pathway Autophagosome Maturation Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Autophagosome Maturation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome Organization Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Peptidyl-lysine Hydroxylation Melanosome Localization Lysosome Localization Collagen Metabolic Process Membrane Fusion Platelet Alpha Granule Organization Autophagosome Maturation
Pathways		Macroautophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Prevention of phagosomal-lysosomal fusion
Drugs
Diseases			Arthrogryposis, renal dysfunction, and cholestasis; ARC syndrome
GWAS		Asthma ( 31619474) HDL cholesterol ( 30275531) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Mean spheric corpuscular volume ( 32888494)	Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Feeling hurt ( 29500382) Hypertension ( 30226566) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566) Red cell distribution width ( 32888494)
Interacting Genes		7 interacting genes: CSNK1A1 MTOR VPS11 VPS16 VPS18 VPS33B ZRANB1	6 interacting genes: APP MAP3K20 MAPK8IP2 TNIP1 UVRAG VIPAS39
Entrez ID		7405	26276
HPRD ID		03929	10541
Ensembl ID		ENSG00000198382	ENSG00000184056
Uniprot IDs		Q9P2Y5	A0A0S2Z577 B7Z1N4 F5H008 Q9H267
PDB IDs
Enriched GO Terms of Interacting Partners?
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