AXL and ADAM10

  • Data Source:
  • HPRD (in vivo)

AXL

ADAM10

Description AXL receptor tyrosine kinase ADAM metallopeptidase domain 10
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 30820047)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Apolipoprotein A1 levels ( 32203549)
  • Chronotype ( 30696823)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Family history of Alzheimer's disease ( 30617256)
  • Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355)
  • Metabolite levels ( 23823483)
  • Schizophrenia ( 30285260)
Interacting Genes 23 interacting genes: ADAM10 CBL EGFR FBXO25 GAS6 GRB2 IL15RA IL2RG LCK MTDH NCK2 PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 RANBP9 SHC1 SHC3 SOCS1 SRC TNS2 TYRO3 7 interacting genes: AXL DLL1 EFNA1 EFNA2 EPHA3 SH3D19 TGFA
Entrez ID 558 102
HPRD ID 00171 03723
Ensembl ID ENSG00000167601 ENSG00000137845
Uniprot IDs M0R0W6 P30530 A0A024R5U5 O14672
PDB IDs 2C5D 4RA0 5U6B 5VXZ 1M1I 6BDZ 6BE6
Enriched GO Terms of Interacting Partners?
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