YJU2 and TRIM15

Data Source:
BioGRID (two hybrid)

		YJU2	TRIM15
Description		YJU2 splicing factor homolog	tripartite motif containing 15
Image			No pdb structure
GO Annotations	Cellular Component	U2-type Catalytic Step 1 Spliceosome	Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator	Mesodermal Cell Fate Determination Regulation Of Gene Expression Protein Ubiquitination Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of RIG-I Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Viral Release From Host Cell
Pathways
Drugs
Diseases
GWAS			Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494) Neurociticism ( 29500382) Neuroticism ( 29255261) Red cell distribution width ( 32888494)
Interacting Genes		22 interacting genes: BANP BRAP CCDC57 CEP70 EMILIN1 FRS2 GAS8 GOLGA2 GOLGA6A JADE1 KAT5 LNX2 MAD1L1 MEOX2 REL TFCP2 TRIM15 TRIM21 TRIM27 ZNF143 ZNF526 ZNF829	39 interacting genes: ACD ACTB AXIN1 CDK6 CFL1 CORO1B CTTN EHMT1 FAM151B FAM161A FAM161B FBLIM1 FERMT2 FERMT3 GAB1 GTF2E1 IRF5 KEAP1 MED7 MSN MYBL2 NEXN PFN1 PRNP PTK2 PXN RABGEF1 ROCK1 SHC1 SNW1 SYK TAF9B TINF2 TRIM8 UBE2U VASP VCL VIM YJU2
Entrez ID		55702	89870
HPRD ID		08546	15551
Ensembl ID		ENSG00000105248	ENSG00000204610
Uniprot IDs		Q9BW85	Q5SRL0 Q9C019
PDB IDs		5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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