PACS1 and KLC2

Data Source:
BioGRID (affinity chromatography technology)

		PACS1	KLC2
Description		phosphofurin acidic cluster sorting protein 1	kinesin light chain 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol COPI-coated Vesicle	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	Protein Binding Ion Channel Binding	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4	16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		55690	64837
HPRD ID		06320	13917
Ensembl ID		ENSG00000175115	ENSG00000174996
Uniprot IDs		A0A024R5H6 Q6VY07	Q9H0B6
PDB IDs			3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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