PRIM1 and MRPL38

Data Source:
HPRD (two hybrid)

		PRIM1	MRPL38
Description		DNA primase subunit 1	mitochondrial ribosomal protein L38
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GO Annotations	Cellular Component	Nucleoplasm Alpha DNA Polymerase:primase Complex Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	DNA Primase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Asthma ( 31619474) Height ( 31562340) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menopause (age at onset) ( 22267201 26414677) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010)
Interacting Genes		4 interacting genes: MDC1 MRPL38 PRIM2 TP53	21 interacting genes: ARHGAP9 BAG3 BEX2 CCDC120 CENATAC CSNK2A1 DOCK8 ENKD1 ERCC6 ERG28 GADD45GIP1 GOLGA6A HSPB3 LONRF1 MKRN3 MRPL18 MYOZ3 PPP1R18 PRIM1 RALY TSEN54
Entrez ID		5557	64978
HPRD ID		08899	14758
Ensembl ID		ENSG00000198056	ENSG00000204316
Uniprot IDs		P49642	Q96DV4
PDB IDs		4BPU 4BPW 4BPX 4LIK 4LIL 4MHQ 4RR2 5EXR 6R4S 6R4T 6R4U 6R5D 6R5E 6RB4	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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