MUC7 and GALNT12

Data Source:
HPRD (in vitro)

		MUC7	GALNT12
Description		mucin 7, secreted	polypeptide N-acetylgalactosaminyltransferase 12
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Lumen Plasma Membrane Extracellular Exosome	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Killing Of Cells Of Other Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	O-glycan Processing Protein Phosphopantetheinylation
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	Defective GALNT12 causes colorectal cancer 1 (CRCS1) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Diabetic nephropathy in type 1 diabetes ( 31537649)	Asthma ( 31959851) Brain morphology (MOSTest) ( 32665545) FEV1 ( 30804560) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		8 interacting genes: AMY1A GALNT10 GALNT12 GALNT14 HTN3 LTF PCGF1 SELL	16 interacting genes: APP BMPR1A BUB1 CDH1 CDKN2A FBXW7 MLH3 MSH2 MUC1 MUC2 MUC5AC MUC7 PIK3CA PMS2 RB1 SRC
Entrez ID		4589	79695
HPRD ID		11759	13561
Ensembl ID		ENSG00000171195	ENSG00000119514
Uniprot IDs		Q8TAX7	Q8IXK2
PDB IDs			6PXU
Enriched GO Terms of Interacting Partners?
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