MUC7 and GALNT10

Data Source:
HPRD (in vitro)

		MUC7	GALNT10
Description		mucin 7, secreted	polypeptide N-acetylgalactosaminyltransferase 10
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Lumen Plasma Membrane Extracellular Exosome	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Killing Of Cells Of Other Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Protein O-linked Glycosylation O-glycan Processing Protein Phosphopantetheinylation
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Diabetic nephropathy in type 1 diabetes ( 31537649)	Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 21701570 25673413 23583978) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549)
Interacting Genes		8 interacting genes: AMY1A GALNT10 GALNT12 GALNT14 HTN3 LTF PCGF1 SELL	3 interacting genes: CNOT2 MUC1 MUC7
Entrez ID		4589	55568
HPRD ID		11759	12157
Ensembl ID		ENSG00000171195	ENSG00000164574
Uniprot IDs		Q8TAX7	Q86SR1
PDB IDs			2D7I 2D7R
Enriched GO Terms of Interacting Partners?
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