PIP4P2 and ZFYVE27

Data Source:
BioGRID (two hybrid)

		PIP4P2	ZFYVE27
Description		phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2	zinc finger FYVE-type containing 27
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Late Endosome Membrane	Nucleoplasm Endoplasmic Reticulum Cytosol Integral Component Of Endoplasmic Reticulum Membrane Axon Dendrite Growth Cone Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity	Protein Binding Identical Protein Binding Protein Self-association Metal Ion Binding
	Biological Process	Phosphatidylinositol Dephosphorylation Negative Regulation Of Phagocytosis	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		5 interacting genes: GTF2IRD1 NEDD4L SLC10A6 TNF ZFYVE27	18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A
Entrez ID		55529	118813
HPRD ID		13233	15735
Ensembl ID		ENSG00000155099	ENSG00000155256
Uniprot IDs		Q8N4L2	A0A0S2Z627 B7Z6J9 Q5T4F4
PDB IDs			1X4U
Enriched GO Terms of Interacting Partners?
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