ZFYVE27 and TMEM14C

Data Source:
BioGRID (two hybrid)

		ZFYVE27	TMEM14C
Description		zinc finger FYVE-type containing 27	transmembrane protein 14C
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GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Integral Component Of Endoplasmic Reticulum Membrane Axon Dendrite Growth Cone Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Regulation Of Heme Biosynthetic Process
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS			Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	45 interacting genes: ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SDC3 SLC10A6 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27
Entrez ID		118813	51522
HPRD ID		15735	15524
Ensembl ID		ENSG00000155256	ENSG00000111843
Uniprot IDs		A0A0S2Z627 B7Z6J9 Q5T4F4	A0A024R001 Q9P0S9
PDB IDs		1X4U	2LOS
Enriched GO Terms of Interacting Partners?
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