NID1 and LACRT

Data Source:
HPRD (in vitro)

		NID1	LACRT
Description		nidogen 1	lacritin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Secretory Granule
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Collagen Binding Laminin Binding Laminin-1 Binding Proteoglycan Binding	Fibronectin Binding Protein Binding Collagen Binding Growth Factor Activity Laminin-1 Binding Protein N-terminus Binding
	Biological Process	Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Glomerular Basement Membrane Development Basement Membrane Organization	Protein Acetylation Positive Regulation Of Cell Population Proliferation Epithelial Structure Maintenance Positive Regulation Of Macroautophagy Calcium-mediated Signaling Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Calcineurin-NFAT Signaling Cascade Protein Localization To Golgi Apparatus Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Secretion Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Tear Secretion Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Laminin interactions Laminin interactions
Drugs		Urokinase
Diseases
GWAS		Cutaneous nevi ( 21478494) Diverticulitis ( 28585551) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Mean platelet volume ( 32888494) Response to levetiracetam in genetic generalized epilepsy ( 32308125) Urate levels in overweight individuals ( 25811787)
Interacting Genes		21 interacting genes: APP COL13A1 COL1A1 COL4A1 FBLN1 FBLN2 FGA FGB HSPG2 ITGAV ITGB3 LACRT LAMA1 LAMC1 LAMC2 LGALS3BP PLAU PLXDC1 PRELP PTPRF SKIL	6 interacting genes: APP FN1 NID1 SDC1 TGM2 VTN
Entrez ID		4811	90070
HPRD ID		00574	06302
Ensembl ID		ENSG00000116962	ENSG00000135413
Uniprot IDs		P14543	Q9GZZ8
PDB IDs		1NDX
Enriched GO Terms of Interacting Partners?
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