GIMAP5 and AQP3

Data Source:
BioGRID (two hybrid)

		GIMAP5	AQP3
Description		GTPase, IMAP family member 5	aquaporin 3 (Gill blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Multivesicular Body Membrane	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding GTP Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Identical Protein Binding
	Biological Process		Positive Regulation Of Immune System Process Renal Water Homeostasis Water Transport Glycerol Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport Cellular Response To Oxygen-glucose Deprivation
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs			Sennosides
Diseases
GWAS			Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		64 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC35C2 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZFYVE27	28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN
Entrez ID		55340	360
HPRD ID		16280	08970
Ensembl ID		ENSG00000196329	ENSG00000165272
Uniprot IDs		A0A090N8P9 Q96F15	A0A2R8Y2R4 Q92482
PDB IDs
Enriched GO Terms of Interacting Partners?
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