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GIMAP5 and SYT1
Data Source:
BioGRID
(two hybrid)
GIMAP5
SYT1
Description
GTPase, IMAP family member 5
synaptotagmin 1
Image
No pdb structure
GO Annotations
Cellular Component
Lysosomal Membrane
Integral Component Of Membrane
Multivesicular Body Membrane
Cytoplasm
Golgi Apparatus
Plasma Membrane
Synaptic Vesicle
Integral Component Of Synaptic Vesicle Membrane
Axon
Clathrin-coated Vesicle Membrane
Synaptic Vesicle Membrane
Dense Core Granule
Chromaffin Granule Membrane
Presynaptic Membrane
Neuron Projection
Neuron Projection Terminus
Excitatory Synapse
Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
Clathrin-sculpted Glutamate Transport Vesicle Membrane
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Clathrin-sculpted Monoamine Transport Vesicle Membrane
Exocytic Vesicle
Hippocampal Mossy Fiber To CA3 Synapse
Glutamatergic Synapse
Molecular Function
Protein Binding
GTP Binding
SNARE Binding
Phosphatidylserine Binding
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Calcium-dependent Phospholipid Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Protein C-terminus Binding
Syntaxin-1 Binding
Syntaxin Binding
Clathrin Binding
Syntaxin-3 Binding
Identical Protein Binding
Protein Heterodimerization Activity
Calcium-dependent Protein Binding
Low-density Lipoprotein Particle Receptor Binding
Calcium Ion Sensor Activity
Biological Process
Detection Of Calcium Ion
Chemical Synaptic Transmission
Neurotransmitter Secretion
Brain Development
Glutamate Secretion
Regulation Of Dopamine Secretion
Vesicle-mediated Transport
Calcium-ion Regulated Exocytosis
Regulation Of Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Cell Differentiation
Positive Regulation Of Dopamine Secretion
Vesicle Docking
Synaptic Vesicle Endocytosis
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Positive Regulation Of Synaptic Transmission
Protein Heterooligomerization
Regulation Of Synaptic Transmission, Glutamatergic
Membrane Organization
Spontaneous Neurotransmitter Secretion
Cellular Response To Calcium Ion
Synchronous Neurotransmitter Secretion
Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter
Calcium-dependent Activation Of Synaptic Vesicle Fusion
Positive Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Regulation Of Regulated Secretory Pathway
Positive Regulation Of Dendrite Extension
Pathways
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Toxicity of botulinum toxin type B (botB)
Toxicity of botulinum toxin type G (botG)
Neurexins and neuroligins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Chloride levels (
29403010
)
Estimated glomerular filtration rate (
31217584
)
General cognitive ability (
29844566
)
Hand grip strength (
29313844
)
Intelligence (MTAG) (
29326435
)
Lung function (
31902109
)
Lysophosphatidylcholine levels (
31551469
)
Obesity-related traits (
23251661
)
Pulse pressure (
30578418
)
QRS duration (
31251759
)
Sodium levels (
29403010
)
Systemic lupus erythematosus (
28714469
)
Systolic blood pressure (
30224653
)
Interacting Genes
64 interacting genes:
ADGRG3
APP
AQP3
AQP6
ARL13B
BTNL9
CD33
CD53
CLDN7
CREB3L1
CYB561
CYBRD1
DKK4
EBP
EDA
EDA2R
ELOVL4
EMP1
ERGIC3
EVI2B
FAM174A
FAM210B
FATE1
FCER1G
GJA8
GJB3
GORAB
GRAMD2B
IFNGR2
JAGN1
KASH5
KIR3DL3
LAYN
LDLRAD1
LSMEM2
M6PR
MGST2
MGST3
MILR1
MS4A14
PDZK1IP1
PTGES
RETREG3
RNASEK
RNF19B
SCN3B
SHISAL1
SLC10A1
SLC35C2
SMIM3
SPACA1
STOM
STX1A
STX2
STX4
SYT1
TM4SF18
TM4SF19
TMEM31
TMX1
TMX2
TNFRSF19
TSPAN18
ZFYVE27
44 interacting genes:
BNIP2
BTN2A2
CACNA1A
CACNB3
CACNB4
CALM1
CSGALNACT2
CYB5B
FGF1
GIMAP5
GOLM1
HMOX2
IKBKG
IRF3
MIP
NAPB
NEDD4
NR1H3
NR3C1
NRXN1
PPARG
RACK1
RBM14
RIMS1
S100A13
SIN3A
SMAD2
SNAP25
STON2
STX1A
STX2
STX3
STX4
SV2B
SYNCRIP
SYT4
TFAP2A
TMEM14C
TMEM254
TMEM60
TSHR
UBIAD1
ZDHHC17
ZFPL1
Entrez ID
55340
6857
HPRD ID
16280
01710
Ensembl ID
ENSG00000196329
ENSG00000067715
Uniprot IDs
A0A090N8P9
Q96F15
A0A024RBE9
J3KQA0
P21579
PDB IDs
2K45
2K4A
2K8M
2KI6
2LHA
2N1T
2R83
3F00
3F01
3F04
3F05
4ISQ
4V11
6G5F
6G5K
6QNS
6TZ3
6U41
6U4U
6U4W
6ZVN
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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