PPP4C and PPP4R1

Data Source:
HPRD (in vivo, in vitro)

		PPP4C	PPP4R1
Description		protein phosphatase 4 catalytic subunit	protein phosphatase 4 regulatory subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex	Protein Serine/threonine Phosphatase Complex Protein Phosphatase 4 Complex
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)	Lean body mass ( 28552196) Metabolite levels ( 23823483) Platelet distribution width ( 27863252)
Interacting Genes		21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6	5 interacting genes: CEP63 DISC1 HDAC3 PPP4C SASH1
Entrez ID		5531	9989
HPRD ID		03615	05366
Ensembl ID		ENSG00000149923	ENSG00000154845
Uniprot IDs		A0A024R625 P60510	Q8TF05
PDB IDs
Enriched GO Terms of Interacting Partners?
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