PPP4C and PPP4R2

Data Source:
HPRD (in vitro, in vivo)

		PPP4C	PPP4R2
Description		protein phosphatase 4 catalytic subunit	protein phosphatase 4 regulatory subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex	Nucleus Nucleoplasm Cytoplasm Centrosome Protein Phosphatase 4 Complex
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding Protein Phosphatase Regulator Activity Protein-macromolecule Adaptor Activity
	Biological Process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling	MRNA Processing Cellular Protein Modification Process Protein Dephosphorylation RNA Splicing Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Processing of DNA double-strand break ends	Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)	Mitochondrial DNA copy number (white blood cells) ( 30704525) Pulse pressure ( 30224653 30578418) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6	1 interacting genes: PPP4C
Entrez ID		5531	151987
HPRD ID		03615	11453
Ensembl ID		ENSG00000149923	ENSG00000163605
Uniprot IDs		A0A024R625 P60510	C9IZF4 Q9NY27
PDB IDs
Enriched GO Terms of Interacting Partners?
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