IMP3 and MCC

Data Source:
BioGRID (two hybrid)

		IMP3	MCC
Description		IMP U3 small nucleolar ribonucleoprotein 3	MCC regulator of WNT signaling pathway
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Preribosome Small-subunit Processome Mpp10 Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	RNA Binding Protein Binding RRNA Binding SnoRNA Binding	Protein Binding Signaling Receptor Activity
	Biological Process	RRNA Processing	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549)
Interacting Genes		15 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MCC MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 USHBP1 ZNF655 ZYX	79 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792
Entrez ID		55272	4163
HPRD ID		12664	01157
Ensembl ID		ENSG00000177971	ENSG00000171444
Uniprot IDs		Q9NV31	P23508
PDB IDs		2CQJ	6MTU 6MTV
Enriched GO Terms of Interacting Partners?
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