TRIM62 and UTP25

Data Source:
BioGRID (two hybrid)

		TRIM62	UTP25
Description		tripartite motif containing 62	UTP25 small subunit processor component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleoplasm Nucleolus Small-subunit Processome
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Binding RRNA Binding U3 SnoRNA Binding
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Multicellular Organism Development Protein Catabolic Process Protein Destabilization Positive Regulation Of Embryonic Development
Pathways		Interferon gamma signaling	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25	11 interacting genes: AP2M1 APP CEP70 MAGEA11 MEOX2 MID2 MIPOL1 RUFY1 TRIM62 TRIM9 ZBTB10
Entrez ID		55223	27042
HPRD ID		07697	14535
Ensembl ID		ENSG00000116525	ENSG00000117597
Uniprot IDs		Q9BVG3	Q68CQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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