GPATCH2 and DPY30

Data Source:
BioGRID (two hybrid)

		GPATCH2	DPY30
Description		G-patch domain containing 2	dpy-30 histone methyltransferase complex regulatory subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Nuclear Speck	Chromosome, Telomeric Region Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	Nucleic Acid Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Phosphatase Activity	Chromatin Silencing At Telomere Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation
Pathways			PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Diastolic blood pressure ( 28135244 27841878) Energy expenditure (24h) ( 28476931) Familial lung cancer ( 29924316) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Photic sneeze reflex ( 27182965) Resting heart rate ( 27798624) Visceral adipose tissue adjusted for BMI ( 22589738)	Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)
Interacting Genes		5 interacting genes: CSNK2A1 DPY30 MAGEB4 PICK1 TSNAX	33 interacting genes: AK8 AKAP14 ARFGEF1 ASH2L BCAS4 BEND3 CDK17 CFAP91 CHMP2B CREB3L3 DYDC1 DYDC2 FAM136A GPATCH2 GTF2I H3-4 ICA1L KMT2C MRFAP1 OTX1 PRPF3 PRRC2B PSMC3 PSMD14 PXN RSPH3 SETD1A TMCC2 TSPY10 TSPY2 TSPY3 UBC ZFYVE19
Entrez ID		55105	84661
HPRD ID		07657	17434
Ensembl ID		ENSG00000092978	ENSG00000162961
Uniprot IDs		Q9NW75	B4DIS3 Q9C005
PDB IDs			3G36 4RIQ 4RT4 4RTA 6E2H 6PWV
Enriched GO Terms of Interacting Partners?
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