PPP1R7 and CLNK

Data Source:
BioGRID (two hybrid)

		PPP1R7	CLNK
Description		protein phosphatase 1 regulatory subunit 7	cytokine dependent hematopoietic cell linker
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Extracellular Exosome	Cytoplasm Protein-containing Complex Mast Cell Granule
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Enzyme Regulator Activity	Protein Binding Protein-containing Complex Binding
	Biological Process	Positive Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		12 interacting genes: CLNK FER HGS MAPK6 MYH3 PPP1CA PPP1CB PPP1CC SPRED1 TAB1 TNFRSF6B USHBP1	29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		5510	116449
HPRD ID		04192	14720
Ensembl ID		ENSG00000115685	ENSG00000109684
Uniprot IDs		A0A140VK83 Q15435	Q7Z7G1
PDB IDs		6HKW 6MKY 6OBN 6OBP
Enriched GO Terms of Interacting Partners?
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