ATG16L1 and RAB33B

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ATG16L1	RAB33B
Description		autophagy related 16 like 1	RAB33B, member RAS oncogene family
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GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Axoneme Phagophore Assembly Site Membrane	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Identical Protein Binding GTPase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Autophagosome Assembly Protein Transport Macroautophagy Protein Phosphopantetheinylation Negative Stranded Viral RNA Replication	Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Autophagy Protein Transport Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER
Pathways		Macroautophagy Macroautophagy	Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases		Crohn's disease
GWAS		Bilirubin levels ( 31801373 31319653 32084209) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 20570966 22936669 22412388 17435756 17554300 21102463 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688)
Interacting Genes		15 interacting genes: APP ATG5 C3 CSNK2A1 CSNK2A2 DEDD2 GAN NOD1 NOD2 OPTN RAB33A RAB33B SETD7 TRAF3IP3 ZFP36	12 interacting genes: ACVR1 ATG16L1 ATG16L2 ATG5 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6
Entrez ID		55054	83452
HPRD ID		16498	05808
Ensembl ID		ENSG00000085978	ENSG00000172007
Uniprot IDs		A0A024R494 A0A024R4B6 Q17RG0 Q53SV2 Q676U5	A0A494C0Z5 Q9H082
PDB IDs		4GDK 4GDL 4NAW 4TQ0 5D7G 5NPV 5NPW 5NUV 5ZYX	6Y09 6ZAY
Enriched GO Terms of Interacting Partners?
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