RAB33B and USP6

Data Source:
BioGRID (two hybrid)

		RAB33B	USP6
Description		RAB33B, member RAS oncogene family	ubiquitin specific peptidase 6
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen	Cytoplasm Lysosome Plasma Membrane Recycling Endosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Autophagy Protein Transport Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER	Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Intracellular Protein Transport Protein Deubiquitination Protein Phosphopantetheinylation Regulation Of Vesicle-mediated Transport Activation Of GTPase Activity
Pathways		Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS			PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		12 interacting genes: ACVR1 ATG16L1 ATG16L2 ATG5 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6	18 interacting genes: ANKRD11 ANKRD44 APP ATXN7L3 CABP2 CALM2 CDC42 EXOSC8 JAK1 JUN MDFI MYL2 RAB33B RAC1 RIPPLY1 TFIP11 UBC ZNF76
Entrez ID		83452	9098
HPRD ID		05808	06827
Ensembl ID		ENSG00000172007	ENSG00000129204
Uniprot IDs		A0A494C0Z5 Q9H082	P35125
PDB IDs		6Y09 6ZAY
Enriched GO Terms of Interacting Partners?
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